RBR: 50 anos. Parabéns e sigamos adiante, sempre

Potenciais Evocados Auditivos Em Indivíduos Acima De 50 Anos De Idade***** Auditory Evoked Potentials in Individuals over 50 Years

Background: auditory evoked potentials. Aim: to describe the results of brainstem auditory evoked potentials (PEATE), middle latency auditory evoked potentials (PEAML) and cognitive potential (P300) in individuals over 50 years. Method: this study was developed at the Speech and Hearing Investigation Laboratory in Auditory Evoked Potentials of the Speech-Language and Hearing Course of the Depar...

RBR E3-ligases at work.

The RING-in-between-RING (RBR) E3s are a curious family of ubiquitin E3-ligases, whose mechanism of action is unusual in several ways. Their activities are auto-inhibited, causing a requirement for activation by protein-protein interactions or posttranslational modifications. They catalyse ubiquitin conjugation by a concerted RING/HECT-like mechanism in which the RING1 domain facilitates E2-dis...

Estudo Bibliométrico da Produção Científica de Gerenciamento de Riscos entre os Anos de 2000 e 2012

Arabidopsis E2FA stimulates proliferation and endocycle separately through RBR-bound and RBR-free complexes.

Post-embryonic growth in plants depends on the continuous supply of undifferentiated cells within meristems. Proliferating cells maintain their competence for division by active repression of differentiation and the associated endocycle entry. We show by upregulation and downregulation of E2FA that it is required for maintaining proliferation, as well as for endocycle entry. While E2FB-RBR1 (re...

RBR: library-less repeat detection for ESTs

MOTIVATION Repeat sequences in ESTs are a source of problems, in particular for clustering. ESTs are therefore commonly masked against a library of known repeats. High quality repeat libraries are available for the widely studied organisms, but for most other organisms the lack of such libraries is likely to compromise the quality of EST analysis. RESULTS We present a fast, flexible and libra...